Strophanthus gratus - Climbing Oleander - ต้นแย้มปีนัง (ton yem pee-nang)

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Strophanthus gratus - Climbing Oleander - ต้นแย้มปีนัง (ton yem pee-nang)


Strophanthus gratus is a plant species known by the common names "climbing oleander" or "ouabain." Here are some key points about this plant:

  1. Description:

    • Strophanthus gratus is a woody, climbing plant that belongs to the Apocynaceae family.
    • It is native to tropical regions of Africa.

  2. Active Compounds:

    • The plant is known for containing toxic compounds, particularly ouabain, which is a cardiac glycoside.
    • Ouabain has historical significance for its use in traditional medicine and, in more recent times, for its potential application in the study of heart function.

  3. Traditional Uses:

    • In some African traditional medicine, extracts from Strophanthus gratus have been used for arrow poisons and as a remedy for various ailments.
    • The plant has been known for its toxic properties, and its use requires caution.

  4. Cardiac Effects:

    • Ouabain, found in Strophanthus gratus, has been studied for its effects on the heart. It inhibits the sodium-potassium pump and has positive inotropic effects, which means it can increase the force of cardiac muscle contractions.

  5. Botanical Characteristics:

    • The plant features lance-shaped leaves and tubular flowers.
    • The flowers are often white and fragrant.

  6. Caution:

    • Due to its toxic nature, Strophanthus gratus should be handled with care.
    • Ingesting or using extracts from this plant without proper knowledge and supervision can be dangerous.

  7. Medical Research:

    • Compounds from Strophanthus gratus, particularly ouabain, have been studied for their potential therapeutic applications, including in the field of heart disease research.

 Please note that while some of the historical uses of Strophanthus gratus involve traditional medicine, caution should be exercised, and any medicinal use should be under the guidance of knowledgeable healthcare professionals due to the plant's toxic properties.


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